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Price Receives NIH Award for $1.4M
Dr. Chester Price has received a substantial grant from the National Institutes of Health totalling 1.4 million dollars to extend his studies of signaling pathways conserved among bacterial pathogens that impact food safety and security. This study was selected from a national peer-group of approximately 100 grant applications reviewed by the National Institute of General Medical Sciences, section of Prokaryotic Cell and Molecular Biology. The success of this investigator-initiated grant represents a milestone for Dr. Price's research program as it extends his 21 years of continuous peer-reviewed NIH support for an additional four years.
His laboratory group will be significantly expanding into new areas that capitalize on long-standing efforts to establish the fundamental properties of a signaling mechanism known to be important for both survival and virulence in many bacteria. The funded project specifically focuses on the genetic, biochemical and structural analysis of a stress-signaling pathway in the bacterium Bacillus subtilis, which serves as a model for related human pathogens such as Bacillus anthracis, Bacillus cereus, Clostridium botulinum, Listeria monocytogenes and Staphylococcus aureus. The information generated will therefore be applicable to a wide variety of pathogens which are transmitted via food or which pose a particular security threat.